Tanzania contains many large and ecologically significant wildlife parks, including the famous Ngorongoro Crater, Serengeti National Park in the north, and Selous Game Reserve and Mikumi National Park in the south. Gombe National Park in the west is known as the site of Dr. Jane Goodall's studies of chimpanzee behavior.

The government of Tanzania through its department of tourism has embarked on a campaign to promote the Kalambo water falls in southwest Tanzania's region of Rukwa as one of Tanzania's many tourist destinations. The Kalambo Falls are the second largest in Africa and are located near the southern tip of Lake Tanganyika.

Tanzania has considerable wildlife habitat, including much of the Serengeti plain, where the white-bearded wildebeest (Connochaetes taurinus mearnsi) and other bovids participate in a large-scale annual migration. Up to 250,000 wildebeest perish each year in the long and arduous movement to find forage in the dry season. Tanzania is also home to 130 amphibian and over 275 reptile species, many of them strictly endemic and included in the IUCN Red Lists of different countries.Tanzania has developed a Biodiversity Action Plan to address species conservation.